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Practice problem

Substitution (DNA Mutation) — Definition & Examples

By Gabi Slizewska
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An amino acid chart. Non-polar amino acids include alanine, valine, methionine, leucine, isoleucine, proline, tryptophan, and phenylalanine. Basic amino acids include lysine, arginine, and histidine. Acidic amino acids include glutamic acid and aspartic acid. Polar amino acids include tyrosine, threonine, glutamine, glycine, serine, cysteine, and asparagine.

Image by Gabi Slizewska.

A substitution mutation can change the order of amino acids that a DNA sequence codes for. How severe the effects are depends largely on the chemical properties of amino acids. Which of the following would most likely result in the least severe mutation if it was swapped with lysine?

Choose one answer

Type a concept, like “slope” or “photosynthesis”.

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