Concentration (Enzyme Reaction Rates) — Effects & Role

Illustrated · 1 min

When the concentration of substrate increases, the rate of the reaction increases. When there are more substrate molecules, more of the enzyme molecules can bind them and speed up the reaction. When the concentration of the enzyme increases, the rate of the reaction increases. When there are more enzyme molecules, more of the substrate can be bound to form product. However, once all of the enzyme molecules are saturated with (bound to) substrate, an increase in the concentration of either one will not alter the rate of reaction.

Image source: By Gabi Slizewska

Video

(Video) Effect of Enzyme and Substrate Concentration on Enzyme Activity

by Ms Cooper's A level Biology

Check out this video for an awesome explanation on how substrate and enzyme concentrations affect the rate of reaction. Ms. Cooper makes this easy to understand by including some great graphs.

Video

(Video) How to Speed up Chemical Reactions (and Get a Date)

by Aaron Sams on TED-Ed

This funny video shows how chemical reactions can be like getting a date to the dance. Pay close attention to how the scientist speeds up the rate of reaction by changing the "concentration" of students in the school.

Illustrated · 1 min

Enzyme Saturation Point

Enzyme reaction rates depend on how often enzymes come in contact with molecules of the substrate.

Increasing the amount of substrate in a reaction will increase the rate of the reaction because the enzyme runs into more and more substrate. The rate of reaction will increase until it reaches its saturation point.

Image source: By fullofstars [Public domain], via Wikimedia Commons

Increasing the amount of substrate in a reaction will increase the rate of the reaction because the enzymes run into more and more substrates. The rate of reaction will increase until it reaches its saturation point. The saturation point is reached when the enzymes are all occupied and are never searching for substrates. The only way to increase the reaction rate once the saturation point is reached is to increase the amount of enzymes.

Illustrated · 1 min

How Do Concentration Levels Change the Rate of Reaction?

The rate of reaction or reaction rate is a measurement of how fast a reaction occurs.

Most often, we look at how quickly products are being made or how quickly substrates are being used up in order to determine rate.

Reactions go faster when enzymes are involved.

Image source: By István Mihály (Mhy) CC0, via pixabay.com \\ Image source: By Gregory Wilson (Director and cinematographer) CC BY 3.0, via Wikimedia Commons

Let's look at two ways to increase reaction rate.

  1. Increasing Enzyme Concentration ===

Increasing the enzyme concentration will make the rate of reaction increase as long as there is enough substrate available to work on.

If we assume that there is an endless supply of substrate available, the reaction rate will go up in a straight line, as seen below.

Rate of reaction increases when you add more enzymes.

Image source: By Hannah Bonville

  1. Increasing Substrate Concentration ===

Increasing the substrate concentration will increase the reaction rate until all of the available enzymes become saturated, or in use.

Once all of the available enzyme active sites are occupied (have substrate bound to them, forming an enzyme-substrate complex), increasing the substrate concentration further will have no effect on the reaction rate.

Eventually, no matter how much substrate you add, the rate of reaction will max out.

Image source: By GYassineMrabetTalk [Public domain], via Wikimedia Commons

Key Vocabulary:

  1. Enzyme
  2. Reaction
  3. Substrate
  4. Rate

Type a concept, like “slope” or “photosynthesis”.

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