Cytoskeleton — Structure & Function

Interactive · 1 question

How Do Cells Keep Their Shape?

Microfilaments, intermediate filaments, and microtubules form the cytoskeleton.

Microtubules are three times bigger in diameter than their microfilament counterparts.

Microtubules are on the left, while microfilaments are on the right. Motor proteins act on the cytoskeletal structure to create movement.

Image source: By OpenStax CC BY 4.0, via Wikimedia Commons

This structure helps cells keep their shape and it also helps with anchorage and movement (like in muscle cells). This is a massive benefit for animal cells because they don't have the rigid cell wall that plant cells have, which makes them more fragile. In other cells, cilia and flagella, the little tails that help them move around, are also considered to be part of the cytoskeleton.

Try to remember that this structure is quite literally the skeleton of the cell. It's even in the name. Cyto means cell and skeleton means, well, skeleton.

Microtubules are polymers of tubulin proteins and are the largest cytoskeletal fibers. Microfilaments are polymers of actin proteins and are a very important structure for cell movement. Intermediate filaments have a very diverse makeup. They create a more permanent structure which is essential for cell shape and support.

The cytoskeleton is right under the cell membrane in the cytoplasm.

Cytoskeletal fibers are highlighted.

Image source: By LadyofHats [Public domain], via Wikimedia Commons

The cytoskeleton helps with which of the following cell functions?

Choose all correct answers

Illustrated · 1 min

Cellular Structure

A cell's cytoskeleton forms its internal framework, giving it structure and support.

Think of the job your own skeleton does: It holds you up, gives you shape, and helps you move. Cyto means "cell", so a cytoskeleton is just the cell's skeleton, and it does those same jobs.

However, it is not made of bones. It is made of long, stretchy proteins. There are three main types of fibers that make up its structure: microfilaments, intermediate filaments, and microtubules. The fibers are able to rapidly assemble and disassemble to fit the needs of the cell.

The cytoskeleton extends throughout the cell.

The cytoskeleton has been dyed green in this picture. Here, there are about six cells shown (nuclei in blue, cell membranes in red). Notice how the cytoskeletal fibers (green) stretch throughout the cell and look stringy, almost like really thin fibers or dental floss.

Image source: By http://rsb.info.nih.gov/ij/images/ [Public Domain], via Wikimedia Commons

In addition to helping a cell keep its shape, the cytoskeleton is also attached to most organelles. This helps keep the organelles in place and assists with the transport of various molecules throughout the cell.

Aside from support, it also helps with cell motility. This is particularly true of cells that use pseudopods (literally "fake feet") to drag themselves along. Other cells have little tails called cilia and flagella that help them move around. These are also considered to be a part of the cytoskeleton.

The cytoskeleton can extend into parts that stick out of the cell, like pseudopods.

In the case of a pseudopod, the cytoskeletal fibers extend all the way into it, giving it structure. The cell uses the pseudopod to drag itself along. This is most common in single-celled organisms.

Image source: By Janice Haney Carr, Dr. Rodney Donlan, USCDCP [Public domain], via pixnio.com

Illustrated · 1 min

What Does the Cytoskeleton Do?

The cytoskeleton helps maintain the shape and structure of the cell as well as provides a means for transport. For example, let's look at a specific type of cell called a neuron:

Image of a neuron, showing the canonical structure and long projecting axon ending in axon terminals.

Image source: By Notjim CC BY-SA 3.0, via Wikimedia Commons

How does it maintain the shape of its long projecting axon? How does a protein made in the cell body (the soma) get to the axon terminals where it will be used? Well, it's all with the help of the cytoskeleton.

This structure is literally the cell's (cyto) skeleton (skeleton). It helps the cell keep its shape, especially in cells without the support of a cell wall. It also acts as a kind of highway system for transporting things around the cell.

It has three major components:

  • Actin
  • Microtubules
  • Intermediate filaments

All of these major components have their own properties and functions in the cell. For example, the protein actin has the ability to grow and shrink rapidly, and is therefore often used by a cell to extend and retract its plasma membrane to move around. Microtubules are more stable and are often used for cellular shipment of products. Finally, intermediate filaments are the most stable and are often used to maintain a cell's structure. Take a look at the protein filaments in the image below.

Image of a neuron with actin filaments stained red and microtubules stained green

In the image above, actin filaments are in red and the microtubules are in green.

Image source: By 8x57is CC BY-SA 4.0, via Wikimedia Commons

Illustrated · 1 min

Parts of the cell: cytoskeleton. This is the skeleton of the cell. Maintains the cell's shape, anchors organelles, and assists with transport. Made of three parts: microfilaments, microtubules, and intermediate filaments.

Image source: By Gabi Slizewska

Video

(Video) Cells - Cytoskeleton

by Mahalo

The cytoskeleton is found in both eukaryotic cells and prokaryotic cells and is essentially a network of fibers. Specifically, it consists of microfilaments, microtubules, and intermediate filaments.

Its function is to maintain the cell's shape and provide some structural rigidity. This is especially important in animal cells, which don't have the tough cell wall that plant cells have. In addition, it helps the cell move, helps the different components of the cell move around, and assists with separating daughter cells during cytokinesis.

Type a concept, like “slope” or “photosynthesis”.

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